Brain stem glioma in childhood: acute hemiplegic onset.
نویسندگان
چکیده
Two children, age seven and 16 years, are described with the abrupt onset of a pure motor hemiplegia as the initial manifestation of a brain stem neoplasm. Subsequent rapid neurological deterioration localized the lesion to the brain stem and glioblastoma multiforme was diagnosed by surgical biopsy. It is suggested that brain stem gliomas with this unusual presentation are likely to be highly malignant and prone to rapid bulbar deterioration.
منابع مشابه
A novel SLC2A1 mutation linking hemiplegic migraine with alternating hemiplegia of childhood.
BACKGROUND Hemiplegic migraine (HM) and alternating hemiplegia of childhood (AHC) are rare episodic neurological brain disorders with partial clinical and genetic overlap. Recently, ATP1A3 mutations were shown to account for the majority of AHC patients. In addition, a mutation in the SLC2A1 gene was reported in a patient with atypical AHC. We therefore investigated whether mutations in these g...
متن کاملIonic Channels in the Therapy of Malignant Glioma
Glioma is among the deadliest tumors worldwide. Despite its relative low onset incidence, glioma, especially malignant glioma, causes high mortality. Due to the utmost aggressiveness of tumor cells, malignant glioma is almost incurable by conventional therapeutic approaches. Finding new molecular targets, which are responsible for tumor progression, can amplify our understanding about malignant...
متن کاملTranscranial Motor Evoked Potentials of Lower Limbs Can Prognosticate Ambulation in Hemiplegic Stroke Patients
OBJECTIVE To examine the association between motor evoked potentials (MEPs) in lower limbs and ambulatory outcomes of hemiplegic stroke patients. METHODS Medical records of hemiplegic patients with the first ever stroke who received inpatient rehabilitation from January 2013 to May 2014 were reviewed. Patient who had diabetes, quadriplegia, bilateral lesion, brainstem lesion, severe musculosk...
متن کاملRemifentanil-Induced Respiratory Failure in PACU after a Brainstem Tumor Debulking: Acute
Remifentanil is a potent, ultra short-acting μ-opioid receptor agonist with a rapid onset of action in 30-60 seconds, peak analgesic and respiratory effects within 2.5 minutes (min), and rapid clearance (T1⁄2 = 3 min) [1]. It is commonly used as part of a balanced anesthetic in many anesthesia practices as well as in the intensive care unit. Its use is particularly prominent in neuroanesthesia,...
متن کاملBrain Stem Gliomas in Childhood
Brain stem tumors are perhaps the most dreaded cancers in pediatric oncology, owing to their historically poor prognosis, yet they remain an area of intense research. Brain stem tumors account for about 10 to 15% of childhood brain tumors. Peak incidence for these tumors occurs around age 6 to 9 years. The term brain stem glioma is often used interchangeably with brain stem tumor. More precisel...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
دوره 8 3 شماره
صفحات -
تاریخ انتشار 1981